The alteration of expression of iNOS mRNA and ecNOS mRNA in peripheral leukocytes from insulin resistance rats fed with fructose
- VernacularTitle:高果糖诱导的胰岛素抵抗大鼠外周血白细胞iNOS mRNA与ecNOS mRNA表达的变化
- Author:
Ruifeng LI
;
Chenghao GUO
;
Shuzhen WEI
;
Fuqin CHEN
;
Rong CHEN
;
Li LI
;
Yumei LIU
;
Weichen HU
- Publication Type:Journal Article
- Keywords:
Fructose;
Rats;
Insulin resistance;
Peripheral leukocytes;
Nitric oxide synthase
- From:
Chinese Journal of Pathophysiology
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the alteration of expression of iNOS mRNA and ecNOS mRNA in peripheral leukocytes of Wistar rats fed with fructose. METHODS: Wistar rats were randomly divided into the control group ( n =10) and the fructose feeding group( n =10). The fructose feeding group drank 12% fructose water for 6 months. The blood glucose, blood insulin, and the expression of iNOS mRNA and ecNOS mRNA in peripheral leukocytes of rats were determined. RESULTS: The levels of blood insulin ( P