Study on the Preparation Technique of Tanshinone Dispersible Tablets
- VernacularTitle:丹参酮分散片制备工艺研究
- Author:
Rongfeng HU
;
Jiahua WANG
;
Jinfen QIAN
;
Chengyong WANG
;
Hao MENG
- Publication Type:Journal Article
- Keywords:
Radix Salviae Miltiorrhizae;
tanshinone;
tanshinone II A;
dispersible tablet;
orthogonal design
- From:
China Pharmacy
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the preparation technique of tanshinone dispersible tablets.METHODS: Taking the disintegration time - limit, in vitro dissolubility and suspensibility as indices, the formula of tanshinone dispersible tablets was screened by orthogonal design.RESULTS The dispersible tablets could completely disintegrate within 30 seconds and pass through 710m seive mesh, which all conformed to the requiremtes of BP(1993) .The in vitro dissolubility of this product was superior to that of ordinary tablets obviously .CONCLUSION: The preparation technique of tanshinone dispersible tablets is mature and the quality is reliable.