Determination of the Contents of Chlorogenic Acid and Baicalin in Shiwuwei Xiaoyanzhike Oral Liquid and Stability Evaluation
- VernacularTitle:十五味消炎止咳口服液中绿原酸及黄芩苷含量的测定及稳定性考察
- Author:
Yalan HUANG
;
Guanghong SUN
;
Weiguang SUN
;
Xinliang MA
- Publication Type:Journal Article
- Keywords:
Shiwuwei Xiaoyanzhike oral liquid;
chlorogenic acid;
baicalin;
stability;
HPLC
- From:
China Pharmacy
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a method for determination of the contents of chlorogenic acid and baicalin in Shiwuwei Xiaoyanzhike oral liquid .METHODS:HPLC was used,the mobile phase was acetonitrile - acetic acid,the flow rate was 0.8ml/ min and the detecting wavelengths were 326nm and 274nm.RESULTS: The recoveries of chlorogenic acid and baicalin were 96.8% - 104.5% , 94.9% -97.7% and RSD were 1.09% -3.12% , 1.19% -1.76% (n = 3), respectively .CONCLUSION: The method is simple and feasible with a good reproducibility, the RESULTS: can provide a basis for establishing the quality standard of this oral liquid.
