Relationship Between Plasma Insulin,Serum Lipids and Cholelithiasis in Patients With Type 2 Diabetes
- VernacularTitle:2型糖尿病合并胆石症与血胰岛素和脂类代谢的关系
- Author:
Daolin HUANG
;
Changle ZHANG
;
Weilong ZOU
- Publication Type:Journal Article
- Keywords:
Cholelithiasis;
Diabetes;
Insulin;
Insulin resistance;
Lipids
- From:
Journal of Chinese Physician
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the level changes of plasma insulin,serum lipids in type 2 diabetes with cholelithiasis.Methods 159 cases of types 2 diabetic patients was studied during recently 3 years in our department of endocrinology,the levels of blood glucose,plasma insulin and insulin sensitivity index(ISI),serum lipids,apolipoproteins(ApoA 1,B) were measured both fasting and post-prandial,and investigated their correlation between type 2 diabetic patients with cholelithiasis(n=103) and without cholelithiasis(n=56).Results Female was predominated in fifty-six diabetic with cholelithiasis,they had higher triglyceride(TG),fasting or post-prandial insulins,ApoA 1,ApoB,the top body weight index and lower ISI than 103 diabetics without cholelithiasis.There were no significant differences in total cholesterol(CH),HDL-Ch,LDL-Ch,blood glucose concentrations between the groups.Conclusions Obesity,insulin resistance and lipids metabolic disturbance might be related to the development of cholelithiasis in type 2 diabetic patients.