A Study on Expressions of ER and PR in Thyroid Tumors Tissue
- VernacularTitle:雌、孕激素受体在甲状腺肿瘤组织中的表达
- Author:
Ran HE
- Publication Type:Journal Article
- Keywords:
Thyroid cancer;
Estrogen receptor;
Progestogen receptor;
Immunohistochemistry
- From:
Journal of Chinese Physician
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objecitve To observe the relationship between the expressions of the estrogen receptor (ER),progestogen receptor (PR) and tumor infiltration and metastasis in thyroid cancer.Methods By using immunohistochemical method to study the relationship between the expressions of ER and PR in 100 cases of thyroid carcinamas and 28 cases of benign thyroid lesions.Results The positive rates of ER and RP expression were 67 0% and 62 0% respectively in thyroid carcinomas,it had correlation with well differentiation and type of histology but positive expression did not relate to age and sex.The positive rates of ER and PR in the non-metastasized group were 75 4% and 70 5% respectively;significantly higher than that of the metastasized group which were 53 8% and 48 7% respectively (P
