Development of gene therapy in wound healing
- VernacularTitle:创面愈合中基因治疗的进展
- Author:
Biao CHENG
;
Xiaobing FU
;
Zhiyong SHENG
- Publication Type:Journal Article
- Keywords:
Gene therapy;
Wound healing;
Stem cells;
Growth substances
- From:
Chinese Journal of Pathophysiology
2000;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
The basic concept of gene therapy is to introduce a therapeutic gene into a cell, whose expression can improve to healing of wound. To achieve this goal, the suitable therapeutic gene has been selected and delivered into the reparative cell, which is becoming a focal point works about gene therapy in wound healing. There have been several different therapeutic genes and gene transfer strategies that have been used in models of wound healing. This article discusses several methods that have been used to deliver genes encoding growth factor proteins, stem cells into wounds and the advantages/disadvantages of each approach. We hope a safe vectors system to deliver the effectual transgene in wound healing.
