The phenotypic-change characteristics of renal residential cells and its roles in the development of renal diseases
- VernacularTitle:肾脏固有细胞的表型转化特征及其病理生理意义
- Author:
Yu WANG
;
Xiaomei LI
- Publication Type:Journal Article
- Keywords:
Kidney;
Phenotype
- From:
Chinese Journal of Pathophysiology
2000;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Increasing evidence has proved that phenotypic changes occured in residential renal cells during the process of renal diseases. The phenotypic change of mesangial cell plays a key role in the development of glomerular sclerosis, while the phenotypic changes of tubulo-interstitial cells have close relationship with the progress of interstitial fibrosis. Understandings of these phenotypic changes and their regulations may help us know better of the mechanism of renal diseases and find out ways to block the disease development.
