Expression of RAR?/RXR?mRNA in Patients with Psoriasis Vulgaris
- VernacularTitle:寻常型银屑病患者皮损中维A酸受体mRNA的表达
- Author:
Suying FENG
;
Lin LIN
;
Qinxue WU
;
Wuqing ZHOU
- Publication Type:Journal Article
- Keywords:
Receptors,retinoic acid;
Psoriasis
- From:
Chinese Journal of Dermatology
1994;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the level of expression of RAR?/RXR?mRNA in skin lesions of patients with psoriasis vulgaris.Methods The skin biopsies were collected fro mskin lesions in 20cases of psoriasis vulgaris and 10normal controls.Expression o f RAR?/RXR?mRNA was detected by RT -PCR.Results Expression levels of RXR?mRNA were 0.19760?0.0933in epiderm ides from psoriatic lesions,which were markedly lower than those in normal controls(0.5867?0.0132)(P0.05).Conclusion The results indicate that decreased expression of RXR?mRNA might be related to the pathogen esis of psoriasis.
