Value of tumor angiogenesis for the prognosis of patients suffering from colorectal carcinoma without metastasis at the time of laparotomy
- VernacularTitle:肿瘤新生血管形成对无转移大肠癌预后判断的价值
- Author:
Wen LEI
;
Baoming YU
;
Xigeng ZHOU
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Neoplasm metastasis;
Neovascularization, pathologic
- From:
Chinese Journal of General Surgery
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo determine the prognostic value of angiogenesis in non-metastatic colorectal carcinoma at the time of laparotomy.Methods Microvessel counts(MVC) of 58 specimens were investigated by immunohistological staining with a monoclonal antibody against F-Ⅷ RAg. Correlation between MVC, clinicopathologic factors, postoperative local recurrence, and liver metastasis was evaluated.Results MVC correlated positively with postoperative local recurrence(P21, the risk of liver metastasis and local recurrence significantly increased. MVC also correlated with prognosis (P
