Study on the Actions of Seabuckthorn Oil Emulsion Against Chronic Atrophic Gastritis and Gastric Ulcer in Rats
- VernacularTitle:沙棘油乳抗大鼠慢性萎缩性胃炎和胃溃疡作用研究
- Author:
Yanli HUANG
;
Juan XIE
;
Lingyun YANG
- Publication Type:Journal Article
- Keywords:
seabuckthorn oil emulsion;
gastric ulcer;
chronic atrophic gastritis
- From:
China Pharmacy
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the actions of seabuckthorn oil emulsion against chronic atrophic gastritis and gastic ulcer in rats.METHODS:Chronic atrophic gastritis and gastric ulcer models were established in rats and mice and the antiulcer and anti-chronic atrophic gastritis actions of seabuckthorn oil emulsion were determined.RESULTS:Seabuckthorn oil emulsion could obviously prevent gastric ulcer and chronic atrophic gastritis induced by deoxycholic acid and stress and could decrease the index of acute gastric ulcer caused by ligature of pylorus in rats and could oppose the ulcer induced by indomethacin-ethanol significantly in mice.CONCLUSION:The results suggest that the antiulcer and anti-chronic atrophic gastritis actions of seabuckthorn oil emulsion may be related with its protection of the gastric mucosal barrier and neutralization of acid.
