Determination of the Content of Ceftazidime in Renal Dialysate Effluent in Burn Patients
- VernacularTitle:烧伤患者肾脏透析排出液中头孢他啶的含量测定
- Author:
Cai LIN
;
Songqing LIU
;
Qing DAI
;
Hongbin LI
;
Yizhi PENG
- Publication Type:Journal Article
- Keywords:
renal dialysate effluent;
ceftazidime;
HPLC
- From:
China Pharmacy
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To determine the content of ceftazidime in renal dialysate effluent in burn patients.METHODS:HPLC was used.The sample was separated on Bondapak-C18 analysis column with a mobile phase of mixture of methanol-ammonium acetate(17∶83,V/V).The flow rate was 1.0ml/min.The UV detector wavelength was set at 254nm.RESULTS:A linearity was obtained from 0.5~100?g/ml with a good correlation(r=0.9 999).The RSDs of inter-day and intra-day precision were not more than 3.The average recovery was 100.30%.CONCLUSION:The method is simple,rapid and accurate.