Safety and Adverse Drug Reactions of Antongding
- VernacularTitle:安痛定的不良反应与用药安全性
- Author:
Xiang HUANG
;
Ying FENG
;
Wei MEI
;
Jinping WANG
- Publication Type:Journal Article
- Keywords:
Antongding;
severe adverse drug reaction;
bone marrow inhibition;
safety of medication
- From:
China Pharmacy
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the adverse drug reaction(ADR) induced by Antongding and its safety in use.METHODS:According to the organ/system type recommended by WHO,34 cases with ADRs induced by Antongding were classified.The ADRs in this series were analysed concerning clinical manifestations,severity of symptoms and inducing mechanism and the safety of use of Antongding was discussed.RESULTS:8 organs/systems were involved in 34 cases with ADRs,of them,18 cases had moderate and severe ADRs(52.94%).In vitro experiments showed that Antongding could inhibit CFU-GM in man.CONCLUSION:Antongding is apt to induce ADRs,so it has potential risk in use.
