Expression of c-myc, bcl-2 and Apoptosis in the Human Cutaneous Squamous Cell Carcinoma
- VernacularTitle:c-myc、bcl-2与细胞凋亡在人类皮肤肿瘤中表达及意义
- Author:
Chenghai WANG
;
Jinhua WANG
- Publication Type:Journal Article
- Keywords:
Cutaneous,neoplasms;
c-myc;
bcl-2;
Apoptosis
- From:
Journal of Chinese Physician
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinicophathological significance of expressions of c-myc,bcl-1 and apoptosis in the human cutaneous squamous cell carcinoma(SCC) canceration course.Methods The expressions of c-myc proteins,bcl-2 protein and apoptosis were detected in 80 cases of SCC by using TdT-mediated dUTP-biotin nick end labeling and immunohistochemical staining.Results The positive rates of c-myc and bc1-2 proteins were 62.5%,38.8% respectively,in SCC tissue(P