Observation on the Expression of HBV-DNA in the Umbilical Cord Tissuesof the Died Fetus Delivered From Puerpera with Hepatitis Virus B
- VernacularTitle:HBV感染孕妇所产死胎脐带组织中HBV-DNA表达的观察
- Author:
Wei ZHAO
;
Wei LIU
;
Chan LOU
- Publication Type:Journal Article
- Keywords:
Died fetus;
HBV-DNA;
Umbilical cord tissues;
In Situ Molecular hybridization technique
- From:
Journal of Chinese Physician
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the expression of HBV-DNA and whether there were copy of HBV in the umbilical cord tissues of the died fetus delivered from puerpera with hepatitis virus B. Methods 40 cases such died fetus were collected by routine autopsy to obtain umbilical cord tissues.And using in situ molecular hybridization technique detected HBV-DNA. Results For the umbilical cord tissues, there were 40%(16/40) cases detected out HBV-DNA.HBV-DNA mainly localization in the surface of the umbilical cord vessel and in the cytoplasma of the cord vessel's endothelial cells. They were not in the cord vessel's endothelial cells nuclei. Conclusions There were HBV replication in the umbilical cord tissues of the died fetus. But the expression of HBV-DNA in the umbilical cord tissues of the died fetus is not related with the HBV replication status in the pregnant woman veins.
