Pathogenic Mechanism of Infective Brain Edema
- VernacularTitle:感染性脑水肿发生的机理研究
- Author:
Guoyuan ZHANG
;
Rong HUANG
;
Yujia YANG
- Publication Type:Journal Article
- Keywords:
endorphin;
Infective brain edema;
Pertussis bacilli;
Rabbit
- From:
Journal of Chinese Physician
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the pathogenic mechanism of ?-endorphin(?-EP) on infective brain edema(IBE).Methods Experimental IBE was induced by pertussis bacilli in rabbits.Forteen rabbits were divided randomly into two groups:Normal saline group(NS,n=7),pertussis bacilli group(PB,n=7).Water content(WC) in brain tissue and ?-EP were measured in plasma,cerebrospinal fluid(CSF),cortex and hippocampus in two groups respectively.Results WC was singnificantly higher in the PB group than those in the NS groups(P