The Protection of Heping Powder on Indomethacin-Induced Gastric Mucosal Damage in Rats
- VernacularTitle:和平散对消炎痛致大鼠胃粘膜损伤的保护作用
- Author:
Zhenbing LI
;
Hui WANG
;
Liping DI
- Publication Type:Journal Article
- Keywords:
Hoping powder;
Non-steroidal anti-inflammatory drugs;
Gastric mucosal damage;
Rat
- From:
Journal of Chinese Physician
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the protection of Heping powder on indomethacin-induced gastric mucosal damage in rat.Methods We used the indomethacin (20mg/kg) intramuscular injection,it induced gastric mucosal damage model in rats,compared the lesion index of Heping powder(3 dosage groups) and control groups.Superoxide dismutase(SOD) and Malonyl dialdehyde(MDA) levels in blood and gastric homogenate were measured as well.Results Gastric mucosal lesion index of all Heping powder dosage groups was obviously reduced(P