Application of Hotelling T~2 Test in analysis of the efficacy of new drug
- VernacularTitle:Hotelling T~2梯方检验在新药疗效中的应用
- Author:
Guoqiang XIONG
;
Pingfan WANG
;
Jianqin LUO
- Publication Type:Journal Article
- Keywords:
OBESITY/drag ther;
SIBUTRAMINE/ther use;
HOTELLING T2 TEST
- From:
Chinese Journal of General Surgery
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Hotelling T2 Test was used to analyze the effect of sibutramine and to provide some information for new drug's exploration. Method Fifty-five patients with body mass index (BMI) over 25kg/m2 were selected according to generally accepted including and excluding criteria. The subjects were divided into 2 groups randomly. Control group was given placebo, and the experimental group were given sibutramine. Biological and biochemical indexes were examined pre-,during and post- clinical trial. Hotelling T2 test was used to compare the index mean vector of different phases. Results There were significant statistical differences between the two groups. (P
