KAI1/CD82 protein expression in human hepatocellular carcinoma and its relationship with invasion and metastasis
- VernacularTitle:KAI1/CD82蛋白表达与肝细胞癌侵袭转移
- Author:
Weiguo ZHANG
;
Yi WANG
;
Weiqing WU
- Publication Type:Journal Article
- Keywords:
Carcinoma,hepatocellular;
Neoplasm metastasis;
Tissue microarrays
- From:
Chinese Journal of General Surgery
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the relationship between KAI1/CD82 protein expression in human hepatocellular carcinoma (HCC) and invasion and metastasis.MethodsSpecimens from primary hepatocellular carcinoma (155 cases), tumorous emboli (22 cases), intrahepatic satellite metastases (4 cases), extrahepatic metastases (16 cases), and normal livers (5 cases) for which a tissue microarray was constructed and used for immunohistochemical detection of KAI1/CD82 protein expression. ResultsImmunohistochemical analysis of tissue microarrays demonstrated KAI1/CD82 protein expression in 61%(95/155)of the primary HCCs and only in 32%(7/22) of the tumorous emboli ( P
