Anti-inflammatory and Analgesic Actions of Essential Oil Extracted From Radix Angelica Sinensis by Ethanol
- VernacularTitle:乙醇提取新鲜当归油的抗炎镇痛作用
- Author:
Linna LIU
;
Min JIA
;
Qibing MEI
;
Tiehong YANG
;
Qingwei WANG
- Publication Type:Journal Article
- Keywords:
essential oil from Radix Angelica Sinensis;
anti-inflammation;
analgesia
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the analgesic and anti-inflammatory actions of essential oil extracted from Radix Angelica Sinensis METHODS:The pharmacodynamic effects were obsersed in five experimental models of inflammation and pain,including:(1)mouse auricular edema induced by xylen;(2)increased vascular permeability induced by acetic acid in mice;(3)paw edema caused by albumen in rats;(4)granuloma caused by implanted cotton ball in rats;(5) writhe reaction induced by acetic acid in mice RESULTS:Essential oil from Angelica Sinensis could distinctively inhibit the inflammatory edema caused by various inflammatory agents and reduce the times of writhe induced by acetic acid in mice CONCLUSION:Essential oil from Angelica Sinensis has analgesic effect and could not only inhibit acute inflammation but also chronic ones in animals
