A Study on Role of Viruses Infection in Pathogenesis of Nephrotic Syndrome
- VernacularTitle:病毒感染在小儿肾病发病机制中的作用研究
- Author:
Lifang MU
;
Zheng WANG
;
Shuping JI
- Publication Type:Journal Article
- Keywords:
Nephrotic syndrome;
Viruses gene;
Child
- From:
Journal of Chinese Physician
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore whether respiratory tract viruses infection was involved in the pathogenesis of steroid sensitive and simple nephrotic syndrome(SSSNS).Methods Expression of respiratory tract viruses gene and antigen in peripheral blood mononuclear cells(PBMC) and production of viruses antibody in sera from 26 children with steroid-sensitive and simple nephrotic syndrome were evaluated by reverse transcription polymerase chain reaction(RT-PCR),APAAP and ELISA.Results In compared in active phase with remission group of SSSNS and normal age-matched controls,the positive rate of viruses of active phase group was significantly increased(P
