The regulatory activity of the lately cloned promoter PLUNC-p in transgenic Xenopus Laevis
- VernacularTitle:用非洲爪蟾分析新调控子PLUNC-p组织调控特性
- Author:
Ling ZHANG
;
Xiangling FENG
;
Wen ZHOU
;
Hong LI
;
Jianling SHI
;
Kaitai YAO
- Publication Type:Journal Article
- Keywords:
Xenopus;
Genes;
Promotor regions (Genetics)
- From:
Chinese Journal of Pathophysiology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: Our study focused on investigation of tissue specific regulatory activity of the newly cloned promoter: PLUNC-p with driving enhanced green fluorescent protein ( EGFP ). METHODS: Transgenic Xenopus Laevis system was applied.RESULTS: The green fluorescence protein directed under PLUNC-p was expressed strictly in branchial arches and epidermis of Xenopus Laevis embryos while CMV promoter showed ubiquitous regulation characteristic.CONCLUSION: PLUNC-p is able to direct epithelia specific expression of EGFP . This property of PLUNC-p might raise the possibility that lead target genes to express tissue-specifically.