Bile pathogen detection and antibiotic drug sensitive test in patients with cholelithiasis
- VernacularTitle:胆石病的胆汁病原菌培养及药敏分析
- Author:
Guanrui YE
;
Meirong LI
;
Shurong LU
- Publication Type:Journal Article
- Keywords:
Cholelithiasis;
Bile;
Microbial sensitivity tests
- From:
Chinese Journal of General Surgery
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the spectrum of bile pathogen in patients with cholelithiasis and their drug sensitivity to antibiotics.Methods Microbes automatic detection system was applied to detect the spectrum of bile pathogen and their drug sensitivities in 366 cholelithiasis patients who underwent choledochotomy. ResultAmong 366 specimen ,common cultures were positive in 258 (70 5%) in which 268 strains of aerobes were detected, and most of them were E.coli(121 strains,45 2%), Klebsiella pneumoniae (24 2%) and Enterococcus(10 1%). 14 strains of anaerobes were cultured in 32 specimen with an incidence of 44%,among which the most common type was B.fragilis (57%).Most pathogens in all the bile specimen were gram negative,73% in aerobes and 86% in anaerobes. Aerobes were highly sensitive to imipenem, tazobactam/piperacillin (TZP) and amikacin, with sensitive rate of 94%,83%, and 63%, respectively. The sensitive rate of anerobes to imipenem as well as TZP was 93% and 86% repectively. Conclusions The main pathogen in patients with cholelithiasis were Escherichia coli,Klebsiella pneumoniae, intestinal cocci and B.frailis which were most sensitive to those antibiotics such as imipenem and TZP.
