The evaluation of PowerPlex~?6 used in paternity testing
- VernacularTitle:PowerPlex~(TM) 16体系在亲子鉴定中的应用评估
- Author:
Hongyu SUN
;
Xinyao WU
;
Yanhong ZENG
- Publication Type:Journal Article
- Keywords:
Forensic science;
Multiplexing;
Paternity testing
- From:
Chinese Journal of Forensic Medicine
1988;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the power of the PowerPlex?6 system for paternity testing. Method 633 cases of paternity testing were studied. After the megaplex STR amplification, the PCR products were genotyped by using the ABI377 DNA Sequencer. Results Among the 879 unrelated individuals, 197 alleles and 739 different genotypes were observed. The cumulated discriminating power was 1x 10-30. And the cumulative chance of exclusion was 0.999999999999987. 95 out of 633 cases were excluded. The RCP of all unexcluded cases were ≥0.9990. Gene mutations were found in 19 cases. Conclusion The Po-werPlex?16 system is powerful and reliable for paternity testing.
