Preparation of Compound Fluconazole Eye Drops and Determination of the Content of Fluconazole in the Preparation
- VernacularTitle:复方氟康唑滴眼液的制备及含量测定
- Author:
Enjuan ZHANG
;
Hua TIAN
;
Baixin CHEN
- Publication Type:Journal Article
- Keywords:
fluconazole;
eye drops;
preparation;
determination of content
- From:
China Pharmacy
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish the method for preparation of compound fluconazole eye drops and to determine the content of fluconazole in the preparation METHODS:Detection was performed by second order derivative spectrophotometry RESULTS:Linear relationship was found in the fluconazole concentrations ranging from 80?g/ml to 400?g/ml The regression equation was D=0 0 094+0 002C,r=0 9 998 The recovery of fluconazole was 99 83%(RSD=0 69%,n=5) CO_NCLUSION:The eye drops was stable The method of determination of the content is simple,rapid and reliable
