Expression of a oncogene signal transducer and activator of transcription 3 (Stat3) and its relation to clinicopathological features of colorectal cancer
- VernacularTitle:癌基因Stat3与结直肠癌临床病理特征的关系
- Author:
Xiangtao MA
;
Shan WANG
;
Ruyu DU
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Signal transduction;
Transcription factors
- From:
Chinese Journal of General Surgery
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of a novel oncogene Stat3 in colorectal cancer. Methods Western blot analysis was performed on cancerous and normal colonic tissue of 45 patients with colorectal carcinoma. ResultsStat3 protein level increased in colorectal cancer compared with adjacent normal mucosa ( P
