The changes of immune function after hepatectomy for hepatocellular carcinoma in cirrhotic patients
- VernacularTitle:肝癌合并肝硬化患者肝癌切除后机体免疫状态的变化
- Author:
Zhixin CAO
;
Xiaoping CHEN
;
Zaide WU
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
Liver cirrhosis;
Hepatectomy;
T lymphocyte subsets
- From:
Chinese Journal of General Surgery
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the changes of immune function after hepatectomy for hepatocellular carcinoma(HCC) in patients with liver cirrhosis.MethodsPatients with liver cirrhosis were used as control group,CD4?CD8?CD4/CD8? and protein expression level of IFN ??IL2?IL10 in peripheral blood from 18 advanced HCC cases with liver cirrhosis before and after heaptectomy were detected by flow cytometry(FCM) and ELISA.Results Postoperative CD4(33?3)%?CD4/CD8(1 1?0 1)?IL2(71?11)?pg/ml?IFN ?(90?15)?pg/ml level elevated compared to that of pre operation 〔CD4(29?4)%?CD4/CD8(0 9?0 3)?IL2(57?15)?pg/ml?IFN ?(78?13)?pg/ml〕(all P
