Research on the Expression of Cyclin E and P27~(kip1) in Bladder Transitional Cell Carcinoma and its Relation With the Expression of Ki-67
- VernacularTitle:Cyclin E和p27~(kip1)在膀胱移行细胞癌中表达及与Ki-67表达的关系
- Author:
Dengke YANG
;
Shukui CHEN
;
Wei HU
;
Al ET
- Publication Type:Journal Article
- Keywords:
Bladder transitional cell carcinoma;
Gene expression,cyclin E,p27 kip1;
Ki-67;
Immunohistochemistry
- From:
Journal of Chinese Physician
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of cell cycle regulating protein cyclin E and p27 kip1 in bladder transitional cell carcinoma (BTCC) and to evaluate its relation with the expression of Ki-67.Methods With immunohistochemistry assay , the expressions of cyclin E , p27 kip1 and Ki-67 were examined in 65 cases of BTCC and 12 cases of normal bladder tissue as controls.Results There was a positive correlation between cyclin E expression and the pathological grade(P
