Child and Adolescent Onset Obsessive Compulsive Disorder.
- Author:
Boong Nyun KIM
1
Author Information
1. Division of Child & Adolescent Psychiatry, Department of Psychiatry, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Review
- Keywords:
Child and adolescent OCD;
Epidemiology;
Clinical features;
Neurobiology;
Treatment
- MeSH:
Adolescent*;
Adult;
Antipsychotic Agents;
Basal Ganglia;
Child*;
Epidemiology;
Genetic Linkage;
Humans;
Male;
Neurobiology;
Neuroimaging;
Obsessive-Compulsive Disorder*;
Prevalence;
Sex Ratio;
Statistics as Topic;
Tic Disorders
- From:Korean Journal of Psychopharmacology
2003;14(2):119-128
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Obsessive compulsive disorder with child & adolescent onset (C-OCD) is not a rare disorder. Though OCD patients with prepubertal onset is scarce, the prevalence of OCD with postpubertal, adolescent onset reach nearly that of adult OCD. In clinical features, C-OCD resemble adult OCD. However, the other features of pediatric OCD are different from those of adult OCD. The sex ratio of pediatric OCD is male dominant and C-OCD show high comorbid rate with tic disorder, which is not prevailing in adult OCD. Family data analysis of tic disorder and C-OCD reveal the close genetic linkage between two disorders. Neuroimaging studies of C-OCD indicate very consistent findings in basal ganglia volume change (usually reduction of striatum) that may not be so consistent in adult OCD. SSRIs are less effective in C-OCD and combined therapy with antipsychotics is more frequently needed than adult OCD. In conclusion, child and adolescent OCD can be a distinctive subtype of OCD that is different from adult OCD in many ways.
