The application of DWI and ADC mapping in acute cerebral infarction and basis of pathophysiology
- VernacularTitle:DWI、ADC图对急性脑梗塞诊断的应用及病理生理基础
- Author:
Li HUANG
;
Xiuhe WANG
;
Sirun LIU
- Publication Type:Journal Article
- Keywords:
Cerebral infarction;
Diffusion weighted imaging;
Apparent diffusion coefficient
- From:
Chinese Journal of Pathophysiology
1989;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the roles of isotropic diffusion weighted imaging(DWI)and apparent diffusion coefficient(ADC)mapping in diagnosing early cerebral infarction.METHODS: 21 patients with cerebral in farction (8hyperacute,13 acute)were imaged with both conventional MRI and single-shot echo-planar isotropic diffusion weighted imaging.Among them 12 patients had CT scanning simultaneously within 24 hours after onset.The positive rate of early infarction was comparted on CT,T 2WI and DEI.The change of the infarct lesion in DWI and T 2WI was also analysed.The average ADC,relative ADC(rADC)and the ADC from center to periphery of the lesion were calculated.RESULTS: 8 hyperacute cerebral ischemic regions were revealed at DWI and ADC mapping,but CT and conventional MR were not.Hyperacute and acute infarcts appeared as areas of hyperintensity on DWI,and their average ADC was significantly depressed comparted with homologous contralateral tissue (0 698?0 104 ?s 0 990?0 161?10 -3 mm 2/s; P
