Clinical study of recombinant human erythropoietin used in 21 perioperative patients
- VernacularTitle:围手术期应用重组人促红细胞生成素21例的经验
- Author:
Guoqing CHEN
;
Chongzhi ZHOU
;
Zhihai PENG
- Publication Type:Journal Article
- Keywords:
Erythropoietin, recombinant;
Intraoperative period;
Blood transfusion;
Anemia
- From:
Chinese Journal of General Surgery
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of recombinant human erythropoietin (rHuEPO) on anemia and blood transfusion requirements in perioperative patients.Methods21 cases, with abdominal surgery(with anemia before operation or with expected blood loss 400~600?ml were divided into two groups (study group or control group).The patients in the study group received subcutaneously rHuEPO 300?IU?kg -1 ?w -1 starting 2 weeks before operation for 3 times.Results In the study group,RBC,Hgb,Hct significantly increased to 0 36?10 12 /L?13 3?g/L and 3 8% respectively after rHuEPO therapy,intraoperative blood transfusion reduced significantly ( P