The change of serum inflammatory mediators in patients undergoing tension-free inguinal hernia repair
- VernacularTitle:无张力疝修补术后患者血清炎症介质的变化
- Author:
Yachuan FAN
;
Xuejun HE
;
Xuecheng LI
- Publication Type:Journal Article
- Keywords:
Hernia,inguinal;
Surgical procedures,operative;
Inflammation mediators
- From:
Chinese Journal of General Surgery
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveThis study was to evaluate the changes of inflamatory mediators in patients undergoing tension free hernioplasty(LH) using expanded polytetrafluoroethylene (e PTFE) mycromesh biomaterial or conventional Bassini hernia repair(BH). MethodTwenty one patients randomized into two groups receiving LH or BH. Peripheral venous blood samples were collected 24 hours prior to surgery and then 6,24,48 and 168 hours postoperatively.ResultLH patients showed a higher increased serum level of fibringen,C reactive protein,alpha 1 antitrypsin, and interleukin 6 than BH patients. Postoperative visual analogue scales for pain reduced on mobilization for patients undergoing LH compared with BH. Neutrophils significantly increased only in LH compared with baseline. ConclusionOur data show that although LH induces less pain and rapid postoperative recovery,it is associated with an higher inflammatory response compared with BH, likely due to mycromesh biomaterial.
