Determination of the Concentration of Ranitidine in Serum by the Method of Multipled Ultraviolet Coefficient
- VernacularTitle:紫外系数倍率法测定雷尼替丁血药浓度
- Author:
Bingxin LAN
- Publication Type:Journal Article
- Keywords:
multipled ultraviolet coefficient;
ranitidine;
concentration of drug in serum
- From:
China Pharmacy
1991;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To determine the concentration of ranitidine in serum METHODS:To use the method of multipled ultraviolet coefficient,the concentration of ranitidine in serum was scanned with detective wavelengths from 200nm to 400nm,and the work-curve was made with detective wavelengths at 324nm and 358nm RESULTS:Ranitidine taken orally resulted in an obvious double-peak in blood concentration CONCLUSION:The method is simple and quick,and is fit for the determination of serum concentration of ranitidine in basic units