The Effects of Erythropoitin on Anemia of Preterm Infants
- VernacularTitle:促红细胞生成素在早产儿贫血中的治疗作用
- Author:
Li WAN
;
Wei ZHANG
;
Xinghua HUANG
- Publication Type:Journal Article
- Keywords:
Erythropoietin;
Infant,premature;
Anemia
- From:
Chinese Journal of Perinatal Medicine
1998;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To test the effect of EPO on anemia of preterm infant. Methods Thirty preterm infants less than 35 weeks of gestational age from three different hospitals were devided ramdomly into EPO group of 16 cases and control group of 14 cases. The infants in EPO group were received rh EPO 400 IU/(kg?d) subcutaneously twice a week for 4 weeks from 7 days old, together with oral supplementation of ferrous sulfate at a dossage of 3~5 mg/(kg?d) in both groups. Hemoglobin(Hb) and reticulocytes(Ret) were measured at 42 days of age. Results The hemoglobin was higherin the EPO group[(999?29)g/L vs (905?25)]g/L, P 0.05). Conclusion The is lower EPO level in prematures and efficiency of rh EPO in the treatment of anemia of preterm infants. There is no observed substantial adverse effects.
