Investigation of Blood Platelet-activating Factor Levels in Neonatal Hypoxic-ischemic Encephalopathy
- VernacularTitle:新生儿缺氧缺血性脑病时血小板活化因子水平的变化及临床意义
- Author:
Shuyu WANG
;
Fanhang MENG
;
Xiaoping RONG
- Publication Type:Journal Article
- Keywords:
Cerebral anoxia;
Cerebral ischemia;
Infant, newborn;
Plateletactivating factor
- From:
Chinese Journal of Perinatal Medicine
1998;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes of the blood Platelet activating factor (PAF)levels in neonatal hypoxic ischemic encephalopathy(HIE),and explore the relationship between PAF levels and severity of brain damage. Method The levels of blood PAF and SOD were measured in neonates with HIE by radio immunoassay and compared with that of normal term neonates. Results Blood PAF levels were much higher in acute stage of HIE,and PAF levels increased with the severity of HIE.Blood SOD and platelets were much lower compared with PAF. PAF is negatively correlated to SOD and PLT.( r=-0.467 and r=-0.359,P
