Clinical Value of Procollagen Type Ⅲ Aminoterminal Peptide Assay in the Serum of Patients With Congestive Myocardial Failure
- VernacularTitle:充血性心力衰竭患者血清Ⅲ型前胶原氨基端肽检测的临床价值
- Author:
Xi LIANG
;
Rongshen LI
;
Aizhen LIN
- Publication Type:Journal Article
- Keywords:
Congestive heart failure;
Collagen;
Fibrosis,myocardial;
Detection
- From:
Journal of Chinese Physician
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the serum concentration of procollagen type Ⅲ aminoterminal peptide (PⅢP) and laminin(LN) in patients with congestive heart failure(CHF),in order to explore the value in diagnosis of myocardial fibrosis.Methods In 44 patients with CHF and 30 healthy controls,serum concentration of PⅢP and LN were measured by competitive radioimmunoassay.Results Serum concentration of PⅢP in patients with CHF significantly increased,as compared with normal controls(5 5?1 1)?g/L vs (3 8?1 5)?g/L(P