The value of p27 and Ki-67 detection in differentiating benign from malignant thyroid follicular neoplasms
- VernacularTitle:p27及Ki-67对鉴别良、恶性甲状腺滤泡状肿瘤的价值
- Author:
Guilong GUO
;
Zhenxiang YAO
- Publication Type:Journal Article
- Keywords:
THYROID NEOPLASMS/diag;
CARCINOMA,FOLLICULAR/diag;
ADENOMA,FOLLICULAR/diag;
TUMOR MARKERS,BIOLOGICAL
- From:
Chinese Journal of General Surgery
1994;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the value of p27 and Ki-67 detection in differentiating benign from malignant thyroid follicular neoplasms. Methods Labelling index (LI) of thyroid neoplasms from thyroidectomy specimens were detected immunohistochemically Results The normal thyroid group had the highest expression of p27 , and the lowest expression of Ki-67. There was significant difference in the expressions of p27 and Ki-67 between follicular thyroid adenomas (FA) and follicular thyroid cancers (FTC) (P
