Role of mast cell and its subpopulations in simple and irradiated-wound of rats
- VernacularTitle:肥大细胞在单纯和放射复合伤口愈合中的作用
- Author:
Yufang CUI
;
Guowei XIA
;
Xiaobing FU
;
Hong YANG
;
Ruiyun PENG
;
Yabing GAO
;
Xuemei CUI
;
Dewe WANG
- Publication Type:Journal Article
- Keywords:
Mast cells;
Wound healing;
Radiation
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To examine the role and dynamic changes of mast cell(MC) and its subpopulations in simple and irradiated-wound of rats.METHODS:MC and its subpopulations were estimated using alcian blue-safranin (ABS)double staining RESULTS:(1)The total number of MC in two groups decreased coincidently on day 2 after wounding, and the total MC increased rapidly and reached maximal gradually on day 5 and 7 after wounding, the increment of MC remained consistently 28 day after wounding (2)Both mucosal MC( MMC) and Mix MC decreased obviously on day 2 after wounding, hereafter,they remained the low level all the time However, the CTMC kept in the high level after wounding (3)The Mix MC on day 5 and the total MC during day 5-15 after wounding were lower in irradiated group than in simple wound group CONCLUSION: MC and its subpopulations could delay the healing process of simple and irradiated wound
