Effect of Ba~(2+) concentration on L-type Ca~(2+) channel in hypothalamic neurons
- VernacularTitle:大鼠下丘脑神经元L-型Ca~(2+)通道特性与Ba~(2+)浓度关系的研究
- Author:
Qingjie FU
;
Fei ZOU
- Publication Type:Journal Article
- Keywords:
Hypothalamus;
Calcium channels;
Barium
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the effect of Ba 2+ concentration on L-type of Ca 2+ channel in hypothalamic neurons.METHODS: The cell acute isolation technique and cell-attached patch-clamp technique were used. RESULTS : The slope conductance of L-type Ca 2+ channel were 28.6 pS (110 mmol/L) and 19.1 pS (10 mmol/L), and the open probability (NP 0) obviously different with different Ba 2+ concentration as carrier. CONCLUSION: Ba 2+ concentration had the obvious effect on the L-type Ca 2+ channel.
