Genetic polymorphism of human glutathione S-transferase P1 gene among the Han nationality in Guangdong province
- VernacularTitle:广东地区汉族人群的hGSTP1Ile105Val基因多态性的研究
- Author:
Lihong NIE
;
Yiling HU
;
Shengyon WANG
- Publication Type:Journal Article
- Keywords:
Glutathione transferases;
Genetic polymorphism;
Guangdong province
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To analyse the frequencies of individuals of the GSTP1 genotypes among the Han nationality in Guangdong province. METHODS: Polymerase chain reaction-restriction fragment length polymorphism was taken to analyse the GSTP1 genotypes and identify the gene frequencies. RESULTS: The proportion of AA(Ile/Ile),AG(Ile/Val) and GG(Val/Val) genotypes were 57 4%,35 9% and 6 7%, respectively. CONCLUSION: The frequencies of individuals carrying homozygous of the GSTP1 variant allele were 6.7% among the Han nationality in Guangdong province.
