Vascular endothelial growth factor expression in superficial transitional cell bladder carcinoma
- VernacularTitle:多发性浅表膀胱移行细胞癌中VEGF的表达及意义
- Author:
Zhenghui GUO
;
Hua MEI
;
Jian HUANG
;
Siya LI
- Publication Type:Journal Article
- Keywords:
Vascular endothelial growth factor;
Bladder neoplasms
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the expression of the VEGF in single and multiple superficial transitional cell bladder carcinoma and their clinical significance. METHODS: Immunohistochemical method was used to study the VEGF in 60 cases of superficial transitional cell bladder carcinoma and in 10 cases of normal bladder tissue as control. RESULTS: High expression of VEGF in bladder carcinoma cell was observed. The expression level of VEGF in multiple superficial transitional cell bladder carcinoma was higher than that in single superficial transitional cell bladder carcinoma. The recurrent rate in the patient with VEGF high expression was more than that in the patient with VEGF low expression. CONCLUSION: The expression level of VEGF was correlated to the biological behavior of superficial transitional cell bladder carcinoma.