Asymmetric dimethylarginine and atherosclerosis
- VernacularTitle:不对称二甲基精氨酸与动脉粥样硬化
- Author:
Jianzhi LI
;
Qing CHANG
- Publication Type:Journal Article
- Keywords:
Asymmetric dimethylarginine;
Nitric oxide synthase;
Nitric oxide;
Arteriosclerosis
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Asymmetric dimethylarginine(ADMA)is an endogenous inhibitor of nitric oxide synthase(NOS).it reduces nitric oxide production. ADMA is correlated with the risk factors of atherosclerosis, such as hypercholesterolemia, hypertension and hyperglycaemia. Accumulating evidence suggests that a derangement of the NOS pathway plays a critical role in atherogenesis and ADMA may participate in the process.
