Cyclooxygenase and gastrointestinal pathophysiology
- VernacularTitle:环氧合酶与胃肠道病理生理
- Author:
Desheng MENG
;
Jinsheng LU
;
Shilian WANG
- Publication Type:Journal Article
- Keywords:
Prostaglandin-endoperoxide, Gastrointestinal system;
Pathophysiology
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Cyclooxygenase is the key enzymes mediating prostaglandings release. In recent years, two isoforms of cyclooxygenase, a constitutive cyclooxygenase(COX-1)and an inducible cyclooxygenase (COX-2),have been identified, from which people have known more about gastrointestinal pathophysiology. This article is a review of COX-1 and COX-2 on the distribution, inducement and regulation in gastrointestinal tract and its relation to programmed cell death, tumor, ulcer and Crohn's disease.
