Effect of Atropine on Cardiac Autonomic Nervous System
- VernacularTitle:阿托品的心脏自主神经系统效应
- Author:
Zhengxiang XIE
;
Yonghong NIU
;
Zhangyong LI
;
Xiaohong XU
- Publication Type:Journal Article
- Keywords:
atropine;
heart period signal;
spectral analysis;
autonomic nervous system
- From:
China Pharmacy
1991;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the effects of atropine on cardiac autonomic nervous system.METHODS:Using the computerized analysis system developed by our laboratory,the characteristic parameters of heart period signal(HPS)in volunteers were examined before and 1 hour after administrating atropine(0.04mg iv).RESULTS:Atropine could decrease the mean heart period,standard deviation of heart period,high frequency components and total power of HPS spectra,and increase heart rate,relative power of ultra-low frequency components significantly.CONCLUSION:(1)Atropine can decrease standard deviation of heart period or heart rate,which means decreasing irregularity of heart rate.It is the basic reasons why high frequency components of HPS spectra increases,and parasympathetic nervous activity decreases,(2)Atropine can decrease the tonus of parasympathetic nerves,increase the tonus of sympathetic nerves relatively,and decrease the tonus of autonomic nervous system that reveals the decrease of the total power of HPS significantly.
