Study on the Bacterial Endotoxin Test for Lomefloxacin Hydrochloride and Glucose Injection
- VernacularTitle:盐酸洛美沙星葡萄糖注射液细菌内毒素检查法的应用
- Author:
Cuiyan HAN
;
Weiyu ZHAI
;
Guoping CHENG
- Publication Type:Journal Article
- Keywords:
lomefloxacin injection;
limulus test agent;
bacterial endotoxin;
interference test
- From:
China Pharmacy
1991;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the bacterial endotoxin test for lomefloxacin hydrochloride and glucose injection.METHODS:According to the assigned method and guiding principle for bacterial endotoxin test in CHINESE PHARMACOPOEIA 2000,the interference test was performed.RESULTS:Lomefloxacin and glucose injection could interfere with limulus test,however,the interference could be eliminated after adjusting the pH of injection to 6.8～7.0.The proper concentration of limulus test agent of bacterial endotoxin test was 0.25EU/ml.CONCLUSION:Bacterial endotoxin test can be used for quality control of lomefloxacin and glucose injection.
