Effect of iNOS gene transfection via enterocoelia on blood pressure in rats
- VernacularTitle:经腹腔转染iNOS基因对大鼠的降血压作用
- Author:
Qiutang ZENG
;
Kai HUANG
;
Wuqiang ZHU
;
Yuhua LIAO
- Publication Type:Journal Article
- Keywords:
Blood pressure;
Transfection;
Nitric-oxide synthase;
Gene
- From:
Chinese Journal of Pathophysiology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the effect of human iNOS gene transfection on blood pressure in SD rats. METHODS: Human iNOS cDNA was transfected using gene transfection technique via enterocolia. The iNOS gene expression in rat celiac macrophages was also observed. RESULTS: The significant lowering of blood pressure in rats transfected with iNOS gene was observed from second day to sixth day after transfection, compaered to the control group ( P
