The Association of HLA-DQA1 and DQB1 Alleles with Genetic Susceptibility to Psoriasis Vulgaris in Han Chinese
- VernacularTitle:HLA-DQA1及DQB1等位基因与寻常型银屑病遗传易感性研究
- Author:
Xuejun ZHANG
;
Shengcai WEI
;
Zaixing WANG
;
Anping ZHANG
;
Sen YANG
- Publication Type:Journal Article
- Keywords:
Psoriasis;
HLA-DQ antigens;
Alleles
- From:
Chinese Journal of Dermatology
1994;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore HLA-DQA1 and DQB1 alleles in their association with genetic susceptibility to psoriasis vulgaris(PV) in Han Chinese. Method Polymerase chain reaction sequence specific primers (PCR-SSP) method was used to analyze the frequencies of HLA-DQA1 and DQB1 alleles among 189 patients with PV and 273 healthy controls. Results ①HLA-DQA1*0104 and DQA1*0201 alleles were positively associated with PV (Pc
