Intraportal chemotherapy for hepatocellular carcinoma patients with tumor thrombosis of the portal vein
- VernacularTitle:门静脉灌注化学治疗药物治疗肝癌伴门静脉癌栓的临床价值
- Author:
Qiang LI
;
Xishan HAO
;
Zhongguo ZHANG
- Publication Type:Journal Article
- Keywords:
Carcinoma, hepatocellular;
Neoplasm circulating cells;
Drug therapy
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate portal vein chemotherapy for the treatment of hepatocellular carcinoma with portal vein tumor thrombi(PVTT).MethodsFourty five HCC patients with tumor thrombi in the main portal vein or the first branches undergoing surgical resection were divided into two groups receiving postoperative intraarterial and intraportal chemotherapy (21 cases), and intraarterial chemotherapy only (24 cases).ResultsThe survival rates of 6,12,18 months was 86%, 76% and 48% in the treatment group compared with 75%, 58% and 33% in the control group respectively. There were significant difference between the two groups.Conclusion Hepatectomy for HCC with removal of tumor thrombi and transcatheter hepatic arterial and portal vein chemotherapy is an effective treatment for HCC with PVTT.
