Interleukin-2 in its relation with interleukin-12 and soluble interleukin-2 receptor in patients with hepatocellular carcinoma
- VernacularTitle:肝细胞肝癌病人血清IL-12、IL-2、sIL-2R水平的相关性
- Author:
Songqing HE
;
Xiaoping CHEN
- Publication Type:Journal Article
- Keywords:
Cancer, hepatocellular;
Cytokine
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the relationship among serum levels of interleukin-12 (IL-12), interleukin-2 (IL-2), and soluble interleukin-2 receptor (sIL-2R) in patients with hepatocellular carcinoma (HCC).Methods60 patients were randomized into two groups, group A (n=30) received IL-2 (1 MIU?day -1 for seven days), group B (n=30) served as control. Venous blood levels of IL-12?IL-2 and sIL-2R in all patients were measured by enzyme-linked immunosorbent assay (ELISA) before and after the IL-2 administration. Results There was positive correlation between serum levels of IL-2 and IL-12, negative correlation between serum levels of IL-2 and sIL-2R and no correlation between that of IL-12 and sIL-2R. Mean serum levels of IL-12,IL-2 and sIL-2R significantly (P
