Observation of the Influence of pH on Content of Available Iodine and Stability of Providone Solution
- VernacularTitle:pH对聚维酮碘溶液有效碘含量的影响及稳定性观察
- Author:
Jia GAO
- Publication Type:Journal Article
- Keywords:
providone solution;
pH;
content of available iodine
- From:
China Pharmacy
1991;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the influence of pH on the content of available iodine in providone solution METHODS:The pH and available iodine in intermediates and final product of providone were detected and the contents of available iodine before and after adjusting pH were compared RESULTS:Providone solution was unstable in alkaline condition and the content of available iodine gradually decreased with the rise in pH CONCLUSION:In productive process,120% of the labeling quantity of iodine lime should be fed to make sure that the intermediates contain not less than 110% of the labeling amount of iodine,and the pH of intermediates should be controlled in the range of 5 0～6 0
