A summary of the study on the homeobox gene Pem
- VernacularTitle:同源异型框基因Pem研究的概况
- Author:
Lin LIN
;
Yueqin LI
;
Tianhong ZHOU
- Publication Type:Journal Article
- Keywords:
Genes;
Developmental biology
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Pem gene is one of the homeobox gene. Unlike members of Hox gene family, Pem gene is unique located at the proximal end of the X chromosome and its expression has been detected in several immortalized and transformed cells, placenta, embryos and reproductive tissues. Numeral studies showed that its expression is controlled by hormone such as androgen. This review discussed the possible role of Pem in regulating genes involved in the differentiation and development of extraembryonic tissue, spermatogenesis and sperm maturation.